Two field experiments were carried out during seasons at 2020/2021 and 2021/2022 in Etay El-Baroud,  Research Station, El Beheira Governorate, Agriculture Research Center (ARC), Giza, Egypt to study the effect of intercropping two densities of wheat [25% (D1) and 12.50% (D2) with sugar beet as well as sugar beet and wheat in pure stands under eight fertilizer types {100% NPK (T1), 75% NPK + nano-fertilizer of NPK (T2), 75% NPK +bio-fertilizer of NPK (T3), 50% NPK +nano-fertilizer of NPK (T4), 50% NPK +bio-fertilizer of NPK (T5), nano- fertilizer of NPK only, bio-fertilizer of NPK only (T7) and nano- fertilizer of NPK + bio-fertilizer of NPK (T8)}, on sugar beet and wheat. The experiments were designed as split plot design. Results indicated that sowing in pure stand (D3) followed by grown sugar beet under plant density 12.50% of wheat (D2) recorded the highest values of yield and quality of sugar beet in both seasons. All studied characters of sugar beet achieved the highest values with 75% NPK + bio-fertilizer (T3) treatment in both seasons. Top, root and sugar yields/ fed in both season, and sucrose% in 2021/2022 seasons were significantly affected by the interaction between intercropping densities and fertilizer types. The highest values for these characters were obtaned when sowing sugar beet in pure stand (D3) followed by grown under intercropping density 12.50% of wheat (D2) and application of 75% NPK + bio-fertilizer (T3). Sowing wheat in a monoculture crop (D4) recorded the highest values of Plant height (cm), Number of spike/ m2, Grain weight / m2 (g), 1000-grain weight (g) and Grain yield in tons as well as straw yield in tons / fed., followed by grown wheat in intercropping density 25% (D1) in both seasons. Wheat fertilized with 75% NPK + bio-fertilizer (T3) recorded the highest values for all characters in both seasons. Sowing wheat in pure stand (D4), followed by intercropping density 25% (D1) with application of 75% NPK + bio-fertilizer (T3) achieved the highest values of all studied wheat characters in both seasons. LER and K achieved the highest values by using intercropping density 12.50% of wheat with sugar beet and application of 75% NPK + bio-fertilizer, which reached 1.403 and 1.415 as well as 6.602 and 7.124 in the first and second seasons, respectively.