Unraveling the genetic factors underlying sorghum response to drought stress can speed up the development of drought-tolerant sorghum cultivars. To achieve this goal, we evaluated a collection of sorghum bicolor lines and two local cultivars for yield and yield related traits under three different watering regimes (Well-watered = 0.8 Evapotranspiration (ETp), Mild drought stress = 0.6 ETp and severe drought stress = 0.4 ETp.) in two consecutive growing seasons in Egypt. Analysis of variance showed highly significant variations among the tested sorghum genotypes. As an average of all tested genotypes number of grains/head was the most affected trait by drought followed by grain yield / plant, while head length showed the lowest reduction due to drought stress. According to four models viz., Eberhart and Russell's, Perkins and Jinks, Freeman and Perkins and Tai, beside principal component analysis (PCA), Line No. 22 (34.81 g) and cultivar Dorado (33.51 g) were observed as most stable and widely adapted over environments, surprised mean performance for grain yield/plant than grand mean over environments. According to our results the two genotypes (Line No. 22 and cultivar Dorado) can be recommended to be uses under a wide range of environmental conditions and use in breeding programs for development of high yield stable genotypes across environments for future use.