A field experiment was conducted at the Agricultural Research Farm at Al-Kawthar site, Faculty of Agriculture, Sohag University, during the 2018/19 and 2019/20 seasons. This study aimed to study the integrated management of Orobanche weed in faba bean under naturally infested soil conditions. Randomized complete blocks design (RCBD) in a split split-plot arrangement with three replicates was used. Sowing dates were arranged randomly in the main plots, whereas cultivars were allocated randomly in the sub-plots, and then resistance methods were arranged randomly in the sub-sub-plots. Three sowing dates (20th of October, 10th of November and 1st of December), three cultivars (Sakha 1, Giza 843 and Giza 716) and four resistance methods (Herbicide, Intercropping faba bean with fenugreek, Intercropping faba bean with garlic and Without) were used. The obtained results revealed that sowing faba bean at the third date on the 1st of December significantly decreased broomrape infestation (Spikes/m2) and dry weight of broomrape spikes (g/m2) and gave the maximum values of most studied traits in the two seasons, compared with sowing on the 20th of October or 10th of November. Cultivar Giza 843 showed markedly more tolerance to broomrape than other cultivars and gave the lowest values for the number of broomrape (Spikes/m2) and dry weight of broomrape spikes (g/m2) under these conditions, as well as superiority in the most studied traits in both seasons, while cultivar Giza 716 was highly susceptible to broomrape infection. Foliar spraying with glyphosate on the leaves of the faba bean plants significantly decreased broomrape infestation (Spikes/m2) and the dry weight of broomrape spikes (g/m2), and gave the best values of most studied traits compared with the other resistance methods in both seasons. Finally, under naturally infested soil conditions by broomrape in the study area, it could be strongly recommended for sowing Giza 843 cultivar on the 1st of December with foliar spraying by Glyphosate 48% on the leaves of faba bean plants once at the beginning of flowering at a rate of 75 cm3/200 liter per feddan to achieve a higher faba bean crop production in ton per feddan under the conditions of this study.