Background: Chronic non-specific neck pain (CNSNP) is linked to limitations in everyday activities, decreased productivity at work, and a decline in quality of life. Objectives: This study aimed to investigate and compare the effect of deep dry needling (DDN) and muscle energy technique (MET) on pain and function in chronic nonspecific neck pain. Methodology: This randomized control trial randomly assigned 66 patients of both genders with CNSNP aged from 18-40 years to either Group (A) received deep dry needling plus Conventional therapy, Group (B): received MET plus Conventional therapy, and Group (C): received conventional therapy only in a form of Transcutaneous Electrical Nerve Stimulation (TENS), Infrared, and Cervical core stability exercises. This trial evaluated pain intensity using Visual analogue scale (VAS) and functional disability using the Arabic version of neck disability index (ANDI) pretreatment and four weeks after the intervention. Results: Within-group analysis revealed a significant decline in VAS and ANDI post-intervention (p<0.001). Multiple comparison analysis revealed a significant differences between groups, with the major differences favoring group A (p<0.05). Conclusion: In CNSNP patients, DDN and MET are both effective in reducing neck pain and enhancing neck function; however, DDN is more effective, making it preferable treatment