318636

Bucco-adhesive drug delivery systems

Article

Last updated: 05 Jan 2025

Subjects

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Tags

Pharmaceutical Sciences

Abstract

All researchers in the field of pharmacy, and particularly pharmaceutics, always have patient compliance as their top research priority. Currently, there is a lot of researches being done to develop and manufacture a drug delivery system that is safer, more effective, and more patient-compliant. One of those delivery systems is the buccal film dosage form. Fast dissolving films bypass the hepatic system and deliver therapeutic effect/response, making them more palatable and accurate oral dosage forms. Oral films can take the place of over-the-counter (OTC) medications, due to consumer preference and inexpensive cost.  When applied in the oral cavity, a fast-dissolving film quickly becomes hydrated, adheres to the application site, and then dissolves to release the drug. The current review gives a comprehensive overview of the polymers often used in drugs belonging to BCS Classes I through IV as well as factors influencing absorption. For the drugs belonging to BCS Class II and BCS Class III, solubility and permeability are the rate limiting step during the formulation of oral fast dissolving film. Furthermore, this review gives a brief account about the manufacturing methods of oral films.

DOI

10.21608/dusj.2023.318636

Keywords

Oral film, buccal film, patient compliance, polymer, Absorption

Authors

First Name

Ayatallah

Last Name

A. Taelab

MiddleName

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Affiliation

Department of pharmaceutical technology, Faculty of Pharmacy, Delta University for Science and Technology, Egypt

Email

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City

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Orcid

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First Name

Heba

Last Name

I. Elagamy

MiddleName

-

Affiliation

Department of pharmaceutical technology, Faculty of Pharmacy, Delta University for Science and Technology, Egypt

Email

-

City

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Orcid

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First Name

Ebtessam

Last Name

A. Essa

MiddleName

-

Affiliation

bDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Tanta University, Egypt

Email

-

City

-

Orcid

-

Volume

6

Article Issue

2

Related Issue

43625

Issue Date

2023-09-01

Receive Date

2023-09-25

Publish Date

2023-09-01

Page Start

87

Page End

94

Print ISSN

2636-3046

Online ISSN

2636-3054

Link

https://dusj.journals.ekb.eg/article_318636.html

Detail API

https://dusj.journals.ekb.eg/service?article_code=318636

Order

318,636

Type

Original research papers

Type Code

1,769

Publication Type

Journal

Publication Title

Delta University Scientific Journal

Publication Link

https://dusj.journals.ekb.eg/

MainTitle

Bucco-adhesive drug delivery systems

Details

Type

Article

Created At

28 Dec 2024