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399297

Role of miR-7 as Potential Biomarker for Colorectal Cancer

Article

Last updated: 28 Dec 2024

Subjects

-

Tags

Applied and Basic Science.

Abstract

Two-thirds of colorectal cancers (CRCs) occur in more developed parts of the world, making it the third most frequent cancer globally after lung and breast cancers. All racial and ethnic groups are affected by CRC, which primarily affects those 50 years of age and older. This condition may arise as a result of a variety of circumstances, including environmental and hereditary ones. The majority of cases are discovered until after symptoms appear, despite the fact that colorectal cancer screening lowers the frequency of diagnosis at advanced stages. MicroRNAs (miRNA), which are frequently dysregulated in cancer, are crucial for regulating gene expression. Since miR-7 affects the expression of several oncogenes, revealing how miR-7 activity is regulated will probably help us better understand the causes of different types of cancer. The purpose of this study was to look at how miR-7 affects colorectal cancer. We discovered a strong correlation between CRC and miR-7.
miRNA-7 is circulating as a possible non-invasive biomarker for several illnesses and disorders, including colorectal cancer. This study sought to determine whether microRNA-7 may be used as a diagnostic tool for colorectal cancer.

DOI

10.21608/bjas.2024.338935.1539

Keywords

Colorectal cancer : microRNA-7, Potential Biomarker, (CRC)

Authors

First Name

Nourhan M. Attia

Last Name

M. Attia

MiddleName

-

Affiliation

M.Sc Department of Medical Biochemistry & Molecular Biolog - (Faculty of Medicine – Benha University

Email

nourhan.attia.93@gmail.com

City

-

Orcid

-

First Name

Amal

Last Name

A. Hassan

MiddleName

-

Affiliation

Professor of Medical Biochemistry & Molecular Biolog - Benha Faculty of Medicine - Benha University

Email

amal986@hotmail.com

City

Benha

Orcid

-

First Name

Shuzan

Last Name

A. Mohammed

MiddleName

-

Affiliation

Assist. Professor of Medical Biochemistry & Molecular Biology - Benha Faculty of Medicine – Benha University

Email

shuzan.ali@fmed.bu.edu.eg

City

-

Orcid

-

First Name

Emad

Last Name

M. Sarhan

MiddleName

-

Affiliation

Assist. Professor of General Surgery - Benha Faculty of Medicine – Benha University

Email

emad.sarhan@fmed.bu.edu.eg

City

-

Orcid

-

First Name

Lina

Last Name

A. Mohamed

MiddleName

-

Affiliation

Lecturer of Medical Biochemistry & Molecular Biology - Benha Faculty of Medicine – Benha University

Email

lina.mohamed@fapa.bu.edu.eg

City

-

Orcid

-

Volume

9

Article Issue

11

Related Issue

51525

Issue Date

2024-11-01

Receive Date

2024-11-02

Publish Date

2024-11-29

Page Start

73

Page End

77

Print ISSN

2356-9751

Online ISSN

2356-976X

Link

https://bjas.journals.ekb.eg/article_399297.html

Detail API

https://bjas.journals.ekb.eg/service?article_code=399297

Order

9

Type

Original Research Papers

Type Code

1,647

Publication Type

Journal

Publication Title

Benha Journal of Applied Sciences

Publication Link

https://bjas.journals.ekb.eg/

MainTitle

Role of miR-7 as Potential Biomarker for Colorectal Cancer

Details

Type

Article

Created At

28 Dec 2024