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391714

The Role Of MicroRNAs In Psoriasis Vulgaris

Article

Last updated: 28 Dec 2024

Subjects

-

Tags

Applied and Basic Science.

Abstract

Psoriasis is a skin condition that arises from immune cell dysregulation, aberrant neovascularization, and atypical activation of . After transcription, tiny noncoding RNAs called microRNAs mostly influence gene expression. New research reveals that microRNAs are essential in the development of and that their expression is impaired in people with the condition. There is currently a lack of knowledge about the precise roles and action mechanisms of miR-193b in the development of psoriasis. Furthermore, factor and the STAT3 and NF-κB signaling pathways are both inhibited by miR-193b.Psoriasis is a skin condition that arises from immune cell dysregulation, aberrant neovascularization, and atypical activation of . After transcription, tiny noncoding RNAs called microRNAs mostly influence gene expression. New research reveals that microRNAs are essential in the development of and that their expression is impaired in people with the condition. There is currently a lack of knowledge about the precise roles and action mechanisms of miR-193b in the development of psoriasis. Furthermore, factor and the STAT3 and NF-κB signaling pathways are both inhibited by miR-193b.

DOI

10.21608/bjas.2024.328870.1522

Keywords

STAT3 and NF-κB signaling pathways, are both inhibited, by miR-193b

Authors

First Name

nancy

Last Name

MikhaEl

MiddleName

Wadie

Affiliation

Professor of Dermatology, Venereology and Andrology Faculty of Medicine - Benha University

Email

nancywadie@gmail.com

City

-

Orcid

-

First Name

Aliaa

Last Name

Mohamed

MiddleName

-

Affiliation

Assistant Professor of Dermatology, Venereology and Andrology Faculty of Medicine - Benha University

Email

aliaaelhusseiny@gmail.com

City

-

Orcid

-

First Name

Seham

Last Name

Ameen

MiddleName

Gouda

Affiliation

Assistant Professor of Clinical and Chemical Pathology Faculty of Medicine, Benha University

Email

sehamgouda@gmail.com

City

-

Orcid

-

First Name

Samar

Last Name

Gab Alla

MiddleName

Omar

Affiliation

M.B.B.Ch. Faculty of Medicine, Benha University(2007)

Email

dr.samaromargaballah@gmail.com

City

-

Orcid

-

Volume

9

Article Issue

10

Related Issue

51524

Issue Date

2024-10-01

Receive Date

2024-10-01

Publish Date

2024-10-29

Page Start

109

Page End

113

Print ISSN

2356-9751

Online ISSN

2356-976X

Link

https://bjas.journals.ekb.eg/article_391714.html

Detail API

https://bjas.journals.ekb.eg/service?article_code=391714

Order

12

Type

Original Research Papers

Type Code

1,647

Publication Type

Journal

Publication Title

Benha Journal of Applied Sciences

Publication Link

https://bjas.journals.ekb.eg/

MainTitle

The Role Of MicroRNAs In Psoriasis Vulgaris

Details

Type

Article

Created At

28 Dec 2024