Background: Acne vulgaris is a common cutaneous disorder of the pilosebaceous unit with a high prevalence in the general population. Objective: This article aims to review epidemiology, clinical characteristics, diagnosis and treatment of acne vulgaris. Acne affects 9.8% of women and 9.0% of men. However, men are more likely to have this syndrome in adolescence and early adulthood, although this reverses with age. Facial area is most typically afflicted in 99% of cases, followed by dorsal in 60% and thoracic in 15%. Studies that did not meet inclusion requirements were excluded. Ethical approval, eligibility criteria, controls, information, and evaluation measures were study quality assessment factors. A data collecting form was used to independently extract data from each qualifying research for our study results. Lack of a worldwide diagnostic or grading system makes acne prevalence difficult to estimate. Since acne is decreasing owing to therapeutic advances, estimates are revised often. Over 650 million people—9.4% of the global population have acne vulgaris. Medline databases (Pub Med and Medscape) were searched for acne aetiology, pathophysiology, clinical images, and decrease up to 2024.