Background: Mastectomy women always struggle to accept their body after the surgery and become isolated, criticize herself, and unable to use self-compassion as a mean of coping with such adversity.  Aim of the study: This study aimed to examine the correlation between self-compassion and body-image among women with mastectomy. Resarch design: A descriptive correlational design was utilized to achieve the aim of the study.  Setting: The study was conducted at general surgery outpatient's clinics at Benha University Hospital which is affiliated to Ministry of High Education, Benha city, Qalubia Governorate. Subject: A purposive sample of (60) women with mastectomy was utilized in this study. Tools: Three tools were used for data collection: Tool (1): - A- structured interviewing questionnaire sheet included socio demographic as well as clinical characteristics of the studied women. Tool (2):- Self-Compassion Scale (SCS) & Tool (3):- Body-Image Scale. Results: The result of the present study revealed that, the majority of the studied women had low level of self-compassion and the majority of the studied women had poor level of body-image.  Conclusion: There was a high statistically significant positive correlation between mean score of total self-compassion and mean score of total body-image among the studied women with mastectomy. Recommendations:  Psychological intervention should be integrated as a part of routine nursing care to improve their self-compassion and body-image for all women with mastectomy.