Two or more attacks of hypomania, mania, depression, or mixed episodes, interspersed with euthymic intervals, constitute bipolar disorder (BD). Among the leading causes of disability globally, BD is a major concern. Among all mental health illnesses, sexual dysfunction is underestimated and more common in the general population compared to those with mental health issues. The purpose of this article is to provide a comprehensive overview of the sexual abnormalities and behaviors that are often seen in bipolar female patients. Final thoughts: Sexual dysfunctions and abnormal behaviors were more common in women with BD. Manic episodes are associated with increased hazardous sexual conduct in people with BD. Additionally, it was mentioned that couples' sexual pleasure is negatively impacted by hypersexuality during manic episodes and hyposexuality during depressed episodes, and this effect typically continues into the times between episodes. On the other hand, sex may be linked to negative emotions rather than diminished desire during depressed periods. Individuals with mental health illnesses have a greater chance of sexual difficulties damaging personal interactions and quality of life.