Background: Premature Male incontinence is characterised by ejaculation. There is no specific treatment for this illness. Our goal is to look at how individuals with PE who had botulinum-A toxin injections into their bulbospongiosus muscles fared after treatment. Methods: Through percutaneous endovascular injection, ninety outpatients inject five centilitres of botulinum-A toxin diluted with ten centilitres of saline into the bulbospongiosus muscle on each side (PE). The patients were assessed using the Premature Ejaculation Profile scores in conjunction with the intravaginal ejaculatory latency time (IELT) (PEP). Checks again one, three, and six months after the procedure. Without any adverse effects, patients were able to increase their intravaginal ejaculatory delay duration and enhance their PEP score relative to their pretreatment performance. Conclusions. injection A safe and effective method for treating PE involves injecting botulinum toxin into the bulbospongiosus muscle.