This study investigates the antibacterial activity of crude extracts from isolated marine environments that contain the algae Ulva lactuca and Hormophysa. The algal strains' morphological characteristics provide information about their taxonomic identity. Using solvents such as methanol, ethanol, and ethyl acetate, crude extracts were made, and their antibacterial properties were assessed against a variety of bacteria and fungi. While the methanol fractions showed broad-spectrum antibacterial activities, the ethanol fractions had substantial antibacterial activity against Gram-positive bacteria, specifically Bacillus and Staphylococcus aureus. The ethyl acetate fraction of Ulva lactuca showed the best efficacy against Candida albicans, whereas the methanol fractions showed significant antifungal activity against Aspergillus fumigatus. These findings highlight the possibility of Ulva lactuca and Hormophysa algae extracts as viable sources of substitute antimicrobial agents, with various solvents exhibiting varying degrees of efficacy against various bacteria. The methanolic extract of Hormophysa was selected for further discussion because, when compared to other extracts, it had a significant inhibitory impact for the majority of species.