Background: Ankle It is frequently necessary to have surgery in order to get the best possible recovery from fractures, especially lateral malleolar fractures. The purpose of this research was to assess the clinical and radiological outcomes of percutaneous intramedullary screw treatment of lateral malleolar ankle fractures in the early stages. The method was to use intramedullary screws for percutaneous fixation in 25 patients who had lateral malleolar ankle fractures, whether the fractures included the medial or lateral malleoli. Preoperative evaluations were thorough, surgical procedures included closed reduction and screw fixation, and postoperative care was standardised. Complication monitoring, functional grading systems, and radiographic evaluations were all included of the follow-up examinations. The patients' average age was 39.84 ± 8.84 years, and there were 44% females and 56% men. Syndesmotic injuries were present in 32% of patients, whereas transverse fractures accounted for 76% of all fractures. According to McLennan and Ungersma criteria, 96% of patients showed satisfactory decrease in postoperative radiographic examination. In 88% of instances, union was reached within an average of 9.88 ± 1.657 weeks, 8% had malunion, and 4% did not achieve union. The average functional outcome scores, which include AOFAS and modified Olerud and Molander scores, were 85.72 ± 10.13 and 81.24 ± 9.22, respectively. There were little complications; 8% had superficial infections and 12% reported discomfort after the operation. Clinical results, stability, union, and complication rates were all positively affected by percutaneous intramedullary fixation of distal fibular fractures with intramedullary screws.