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331237

Insulin Resistance in Patients with Androgenic Alpoecia”

Article

Last updated: 28 Dec 2024

Subjects

-

Tags

Applied and Basic Science.

Abstract

Androgenic Up to half of men and females are susceptible to androgenetic alopecia (AGA), a genetically determined condition caused by an overreaction to androgens. The loss of scalp hair in male-pattern baldness is related to androgen metabolism and the hair development cycle, both of which insulin is thought to regulate (Nabaie et al., 2009). We found significant differences in insulin, glucose, and HOMA-IR between the patients and controls when we defined hyperinsulinaemia as a fasting serum insulin level of > 10 U/mL. Androgenic alopecia patients had elevated insulin, glucose, and HOMA-IR compared to healthy individuals. This shows that individuals with androgenic alopecia may have unique metabolic profiles, which points to possible underlying mechanisms in the aetiology and evolution of AGA. Based on our findings, we know that HOMA-IR is positively correlated with insulin levels, and that a higher HOMA-IR is strongly linked to being female.The loss of scalp hair in male-pattern baldness is related to androgen metabolism and the hair development cycle, both of which insulin is thought to regulat

DOI

10.21608/bjas.2023.241783.1267

Keywords

androgenic, Alopecia, Insulin, resistance

Authors

First Name

AbdElAziz

Last Name

El Taweel

MiddleName

-

Affiliation

Dermatology, and Andrology Dept., Faculty of Medicine, Benha University

Email

abdelaziz@gmail.com

City

-

Orcid

-

First Name

Rehab

Last Name

Salem

MiddleName

-

Affiliation

Dermatology, and Andrology Dept., Faculty of Medicine, Benha University

Email

rehabmohammed@gmail.com

City

-

Orcid

-

First Name

ola

Last Name

El-Shimi

MiddleName

-

Affiliation

Dermatology, and Andrology Dept., Faculty of Medicine, Benha University

Email

olasamir@gmail.com

City

-

Orcid

-

First Name

Fatma

Last Name

Abdalla

MiddleName

-

Affiliation

Dermatology, and Andrology Dept., Faculty of Medicine, Benha University

Email

drfatma.mahmoud9@gmail.com

City

-

Orcid

-

Volume

8

Article Issue

10

Related Issue

44634

Issue Date

2023-10-01

Receive Date

2023-10-02

Publish Date

2023-10-21

Page Start

99

Page End

102

Print ISSN

2356-9751

Online ISSN

2356-976X

Link

https://bjas.journals.ekb.eg/article_331237.html

Detail API

https://bjas.journals.ekb.eg/service?article_code=331237

Order

14

Type

Original Research Papers

Type Code

1,647

Publication Type

Journal

Publication Title

Benha Journal of Applied Sciences

Publication Link

https://bjas.journals.ekb.eg/

MainTitle

Insulin Resistance in Patients with Androgenic Alpoecia”

Details

Type

Article

Created At

28 Dec 2024