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326007

Serum Plasma Thiol Evaluation in Chronic Telogen Effluvium Patients

Article

Last updated: 28 Dec 2024

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Abstract

Background: Oxidative stress has been linked to chronic telogen effluvium (CTE). In a physiological sense, free radicals are eliminated by thiols, which are powerful and stable antioxidants. When oxidative stress is present, thiols are the body's go-to antioxidant. The purpose of this study is to compare serum total thiol, thiol-disulphide, and disulphide levels in female CTE patients to those of healthy controls. Topics and Approaches: Sixty people with CTE and twenty age- and sex-matched healthy volunteers served as the case and control groups, respectively, in this case-control research. From May 2020 to December 2021, they were scouted from the outpatient clinic of the Dermatology, Venereology, and Andrology Department at Benha University Hospitals. Results: There was no statistically significant difference in age or body mass index between the patients and the controls. In patients, total thiol levels were considerably lower than in controls. Patients had considerably lower levels of thiol-disulphide compared to healthy controls. Patients had considerably lower levels of disulphide compared to controls. The pathophysiology of TE is intimately linked to oxidative stress, we conclude. The development and prevention of oxidative stress are both influenced by the thiol-disulfide equilibrium. TE upsets this delicate equilibrium.

DOI

10.21608/bjas.2023.213086.1175

Keywords

serum, Plasma Thiol Evaluation in Chronic Telogen, Effluvium

Authors

First Name

Ahmed

Last Name

Abdel Wahab Saleh

MiddleName

-

Affiliation

Dermatology, Venerology and Andrology Dept., Faculty of Medicine, Benha University

Email

ahmedabdelwahab14@gmail.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Saber Hussein

MiddleName

-

Affiliation

Dermatology, Venerology and Andrology Dept., Faculty of Medicine, Benha University

Email

mohamed_saber87@gmail.com

City

-

Orcid

-

First Name

Amira Mohamed

Last Name

Noureldin Abdelrahman

MiddleName

-

Affiliation

Clinical and Chemical Pathology Dept., Faculty of Medicine, Benha University

Email

amira_mohamed78@gmail.com

City

-

Orcid

-

First Name

Nehal Gamal

Last Name

Shafiek Mohammed

MiddleName

-

Affiliation

Dermatology, Venerology and Andrology Dept., Faculty of Medicine, Benha University

Email

drnehalgamaldng@gmail.com

City

-

Orcid

-

Volume

8

Article Issue

6

Related Issue

43045

Issue Date

2023-06-01

Receive Date

2023-06-03

Publish Date

2023-06-27

Page Start

107

Page End

110

Print ISSN

2356-9751

Online ISSN

2356-976X

Link

https://bjas.journals.ekb.eg/article_326007.html

Detail API

https://bjas.journals.ekb.eg/service?article_code=326007

Order

86

Type

Original Research Papers

Type Code

1,647

Publication Type

Journal

Publication Title

Benha Journal of Applied Sciences

Publication Link

https://bjas.journals.ekb.eg/

MainTitle

Serum Plasma Thiol Evaluation in Chronic Telogen Effluvium Patients

Details

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Article

Created At

28 Dec 2024