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289058

Evaluation of diabetic changes in the retina in type I diabetes mellitus after 15 to 20 years of its diagnosis

Article

Last updated: 05 Jan 2025

Subjects

-

Tags

Medical and Health Science.

Abstract

Background: Diabetic retinopathy is differentiated into two main types. They are non-proliferative and proliferative diabetic retinopathy. The presence or absence of aberrant new blood vessels is the differentiating characteristic between these two groups (retinal or optic disc neovascularization). The ischemic retina secretes vascular endothelial growth factor (VEGF). We conducted a study to evaluate the diabetic changes in the retina in type 1 diabetes mellitus (T1DM) after 15 to 20 years of its diagnosis using Fundus Fluorescein Angiography & Optical Coherence Tomography Angiography & Optical Coherence Tomography. Methods: The study was designed as a retrospective cohort clinical study conducted on T1DM patients. Results & Conclusion: The most frequent FFA finding was Microaneurysms (51.7%), followed by Cystoid macular edema (CME) (24.1%), while the least frequent findings were an artifact, neovascularization elsewhere (NVE), and branch retinal vein occlusion (BRVO) (3.4% for each). The most frequent OCTA finding was mean FAZ(0.32±0.09mm2) while mean SVD(46.2±4.6%) while mean DVD (46.1±5.6%).The most frequent OCT finding was epi-retinal membrane (16.7%), followed by exudate (13.3%) and intraretinal cyst (10.0%), while the least frequent finding was parafoveal macular edema (3.3%).
Background: Diabetic retinopathy is differentiated into two main types. They are non-proliferative and proliferative diabetic retinopathy. The presence or absence of aberrant new blood vessels is the differentiating characteristic between these two groups (retinal or optic disc neovascularization). The ischemic retina secretes vascular endothelial growth factor (VEGF). We conducted a study to evaluate the diabetic changes in the retina in type 1 diabetes mellitus (T1DM) after 15 to 20 years of its diagnosis using Fundus Fluorescein Angiography & Optical Coherence Tomography Angiography & Optical Coherence Tomography. Methods: The study was designed as a retrospective cohort clinical study conducted on T1DM patients. Results & Conclusion: The most frequent FFA finding was Microaneurysms (51.7%), followed by Cystoid macular edema (CME) (24.1%), while the least frequent findings were an artifact, neovascularization elsewhere (NVE), and branch retinal vein occlusion (BRVO) (3.4% for each). The most frequent OCTA finding was mean FAZ(0.32±0.09mm2) while mean SVD(46.2±4.6%) while mean DVD (46.1±5.6%).The most frequent OCT finding was epi-retinal membrane (16.7%), followed by exudate (13.3%) and intraretinal cyst (10.0%), while the least frequent finding was parafoveal macular edema (3.3%).

DOI

10.21608/bjas.2023.190378.1049

Keywords

diabetic changes in the retina, type I Diabetes Mellitus

Authors

First Name

Mohamed

Last Name

Emam Khattab Barakat

MiddleName

-

Affiliation

Ophthalmology Dept., Faculty of medicine, Benha university

Email

bousha.kimo@gmail.com

City

-

Orcid

-

First Name

Mohamed

Last Name

El Hatew

MiddleName

-

Affiliation

Ophthalmology Dept., Faculty of medicine, Benha university

Email

mohamed.ibrahim03@fmed.bu.edu.eg

City

-

Orcid

-

First Name

Ashraf

Last Name

El Shayeb

MiddleName

-

Affiliation

Ophthalmology Dept., Faculty of medicine, Benha university

Email

ashraf.alshayeb@fmed.bu.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Adel Shebl

MiddleName

-

Affiliation

Ophthalmology Dept., Faculty of medicine, Benha university

Email

ahmed.a.shebl@fmed.bu.edu.eg

City

-

Orcid

-

Volume

8

Article Issue

2

Related Issue

41777

Issue Date

2023-02-01

Receive Date

2023-02-04

Publish Date

2023-02-24

Page Start

101

Page End

106

Print ISSN

2356-9751

Online ISSN

2356-976X

Link

https://bjas.journals.ekb.eg/article_289058.html

Detail API

https://bjas.journals.ekb.eg/service?article_code=289058

Order

34

Type

Original Research Papers

Type Code

1,647

Publication Type

Journal

Publication Title

Benha Journal of Applied Sciences

Publication Link

https://bjas.journals.ekb.eg/

MainTitle

Evaluation of diabetic changes in the retina in type I diabetes mellitus after 15 to 20 years of its diagnosis

Details

Type

Article

Created At

28 Dec 2024