Background: Hemophilia is a bleeding illness characterised by insufficient clotting factors, which may cause significant knee joint injury. Total Knee Joint Replacement (TKJR) has proposed as a promising therapy choice for Hemophilia patients with significant knee joint degeneration, with the goals of restoring joint function and reducing discomfort. Objectives: This study investigates the importance of TKJR in Hemophilia patients, focusing on preoperative concerns, surgical techniques, postoperative treatment, results, and problems exclusive to this community. Conclusions: TKJR has shown to be an effective therapeutic choice for people with significant knee joint degeneration due to haemophilia. Through a multidisciplinary approach, involving hematologists, orthopedic surgeons, and anesthesiologists, along with personalized care and thorough preoperative evaluation, successful outcomes can be achieved. Intraoperative clotting factor replacement therapy plays a crucial role in maintaining hemostasis during surgery. Postoperative management, including pain management, wound healing, and rehabilitation, contributes to functional recovery and improved quality of life. Although Hemophilia-specific complications exist, ongoing research, advancements in surgical techniques, implant materials, and gene therapy hold promise for further enhancing outcomes. Patient education, self-care, and adherence to prophylactic treatment are paramount in achieving long-term success. Continued collaboration and research efforts are necessary to optimize outcomes and improve the lives of Hemophilia patients undergoing TKJR.
Background: Hemophilia is a bleeding illness characterised by insufficient clotting factors, which may cause significant knee joint injury. Total Knee Joint Replacement (TKJR) has proposed as a promising therapy choice for Hemophilia patients with significant knee joint degeneration, with the goals of restoring joint function and reducing discomfort. Objectives: This study investigates the importance of TKJR in Hemophilia patients, focusing on preoperative concerns, surgical techniques, postoperative treatment, results, and problems exclusive to this community. Conclusions: TKJR has shown to be an effective therapeutic choice for people with significant knee joint degeneration due to haemophilia. Through a multidisciplinary approach, involving hematologists, orthopedic surgeons, and anesthesiologists, along with personalized care and thorough preoperative evaluation, successful outcomes can be achieved. Intraoperative clotting factor replacement therapy plays a crucial role in maintaining hemostasis during surgery. Postoperative management, including pain management, wound healing, and rehabilitation, contributes to functional recovery and improved quality of life. Although Hemophilia-specific complications exist, ongoing research, advancements in surgical techniques, implant materials, and gene therapy hold promise for further enhancing outcomes. Patient education, self-care, and adherence to prophylactic treatment are paramount in achieving long-term success. Continued collaboration and research efforts are necessary to optimize outcomes and improve the lives of Hemophilia patients undergoing TKJR.