The purpose of this article is studying the effect of physico-mechanical and fire-resistance of cement composite that contain ZnO-nanoparticles NZnO. ZnO-nanoparticles are prepared by combustion method. The composite cements are prepared with different amounts of NZnO 0.0, 0.1, 0.2, 0.4, 0.6 mass %. From one day to 90 days, the hydration kinetics' behavior was studied. After the specimens were subjected to thermal treatment at 200, 400, 600, 800 and 1000 ^oC, with a rate of heat 5^oC per minute for two hours, the composite cement pastes' thermal resistance was investigated. With a NZnO content of up to 0.6 mass percent, the compressive strength of OPC–NZnO cement pastes increased. The compressive strength of the thermally treated mixes with 0.6 % N-ZnO (NZTU4) is higher than that of the other mixes up to 1000 ^oC. It can be concluded that OPC–N ZnO pastes that contain 0.6 mass% NZnO have an optimal mix composition that has a better firing resistance than those of other pastes.