Background: A series of published articles have reported the epidemiological and clinical characteristics of the hospitalized patients with COVID-19. Most patients reported in the literature were adults, and commonly presented with pneumonia and abnormal findings on chest CT. Elderly patients with comorbidities were more likely to exacerbate with severe and even fatal respiratory diseases such as acute respiratory distress syndrome (ARDS). The number of reported pediatric patients is limited and the clinical characteristics of pediatric COVID-19 was rarely reported. AIM: Studying of the clinical presentation of all pediatric patients admitted with clinical features suggestive or confirmed of Covid-19 infection during hospital stay. METHODOLGY: This is a cross sectional study, which included all the admitted patients meeting the inclusion criteria of suspected or confirmed COVID-19 infection admitted at Benha Fever Hospital during the period of study which will be 6 months. RESULTS: PICU Admission due to System Failure in 30%, mortality rate was 8.3%. Higher TLC, CRP, ferritin were associated with PICU Admission due to System Failure. Non survivors were significantly associated with higher TLC, ALC, CRP and lower oxygen saturation. Conclusion: COVID-19 might influence all body systems causing various clinical presentations varying from mild to life-threatening conditions.