Because aberrant intrauterine growth is related with increased newborn morbidity and death, an accurate estimate of foetal weight is a crucial issue in perinatal treatment. Fetal biometric measures were taken using a 2D ultrasound to determine the birth weight of the baby. The purpose of this study is to compare the reliability of the traditional two-dimensional Hadlock formula for predicting foetal weight to that of three-dimensional ultrasound measurements of foetal thigh volume. Methods: One hundred pregnant women who presented to the Obstetrics and Gynecology department at Benha University Hospital with a singleton live pregnancy between weeks 37 and 40 and no foetal abnormality were included in the research. Patients carrying more than one child, who were in active labour, or who were pregnant with a medical condition were not included in the research. Before anybody took part in the research, they signed informed consent forms. The ranges for anticipated weight using 2D and 3D sonography are (2540–4010) and (2670–3810), respectively. Variations in 3D sonographic thigh volume were seen between (59.62 to 92.52). Comparing the weight predicted by 2D sonography and 3D sonography yielded similar results (P=0.883). Two-dimensional sonography could not accurately predict birth weight (P = 0.582). The discrepancy between the 3D sonographer's estimate and the actual birth weight was not statistically significant (P = 0.403). Actual birth weight was positively correlated with 2D sonography prediction (P 0.001). The actual birth weight was also positively correlated with the anticipated birth weight using 3D sonography (P 0.001). Predicting an expected birth weight for a foetus is aided by measuring the fractional TVol, the authors conclude. Measurements of fractional limb volume may be used to assess foetal size and growth at various stages of pregnancy, and future quantitative investigations should provide light on this topic. Exploring the best birth weight algorithm that adds TVol into conventional birth weight formulas requires large prospective research. Before this indicator may be used in clinical practise, further prospective studies are needed to determine whether or not soft tissue alterations, as measured by TVol, are associated with foetal growth limitation or macrosomia.