Hager M. Younos^1,2, Ahmed E. Salama³, Mohsena A. Abdarrazik⁴ Aim: This aimed to evaluate the pain sensation and the oral hygiene during the treatment of anterior deep bite cases with tooth-borne versus Temporary Anchorage Devices (TADs). Materials and Methods: The sample included sixteen patients with age (15 - 20) years old. They were randomly allocated into two groups, each with eight subjects. Group A a tooth born intrusion used Connecticut Intrusion Arch (CIA) for the maxillary incisor intrusion, and in Group B TADs intrusion by mini-screws were used. The Visual Analogue Scale (VAS) was used for pain evaluation. The Plaque (PI) and Gingival (GI) Indices used to evaluate oral hygiene. Results: There were no statistically significant differences between the two groups regarding age, gender, overbite, ANB and PI to assure the consistency of baseline characteristics.  Regarding the pain evaluation, the differences between the two groups were statistically significant (P=0.018), in group A"CIA" recorded a mean (0.50±.93) and the median value (0), while in group B "TADs" recorded a mean (3.00±2.27) and a median (3). Regarding GI, group B "TADs" recorded a higher mean (0.50±0.53) and median value (0.5), in comparison to Group A"CIA" which recorded a mean (0±0) and a median (0) which was statistically significant difference. Conclusion: There was good oral hygiene maintenance for both systems. However, the pain scale and GI were higher in group B "TADs" causing clinical discomfort and less tolerance in comparison to group A "CIA".