Aim: This crossover study was done to evaluate the maximum biting force and chewing efficiency of digital complete dentures constructed using two different workflows: a combination of intra-oral and facial scanning and an indirect technique. Also, the study compared the two measured parameters of both digital workflows against those of conventional complete dentures.  Materials and methods: Twelve completely edentulous patients received three complete dentures: a conventional complete denture (CD1), a digital complete denture constructed using the indirect workflow (CD2), and a digital complete denture constructed using the combined intra-oral and face scan workflow (CD3). The design of the study was a crossover, with patients wearing dentures in a random order. Biting force and chewing efficiency results were evaluated after three months of using each denture type. Results: There were statistically significant differences in maximum biting force and chewing efficiency between CD1 and each of CD2 and CD3. However, the differences between CD2 and CD3 were statistically insignificant regarding both parameters studied. Conclusion: Within the limitations of this study, digital complete dentures demonstrated higher maximum biting force and chewing efficiency than conventional complete dentures. Furthermore, the differences between the indirect digital workflow and intra-oral scanning combined with the face scanning workflow were statistically insignificant in both parameters.