Objectives: The aim of this systematic review to evaluate the effect of diabetes on dental implants loss .
Data Sources: Review authors searched 3 electronic databases; Pubmed, Cochrane and Lilacs: 11/10/2018, hand searched 11 journals till November 2018 and snowballing: 15/10/2018.
Eligibility criteria: Adult female and male patients above 18 years old, either completely or partially edentulous, maxillary and/or mandibular dental implants, restored by fixed or removable prosthesis, were included. Surgical modifications, drugs that affect bone density, like vitamin D and biphosphonates, were excluded. Diabetic patients, who are classified either controlled or uncontrolled were considered eligible.
Data Collection and Analysis: Review authors extracted data relevant to PECOT. Data was descriptively and statistically analyzed.
Results: A 14 studies; 9 prospective and 5 retrospective studies, involving 1398 participants and 3282 implants, were included in this systematic review. 3 studies were included in the meta-analysis.
Conclusion: Based on the results of implant loss 2 years following implant placement, implant therapy in diabetic patients seems to be possible. However, results should be taken with extreme cautions, since the quality of evidence is very low.