The present study was designed to investigate the curative effect of date palm and date biscuits on gastric ulcer. The effect of date and date biscuits on the nutritional and gastric ulcer healthy status. Thirty adult albino male rats Sprague –Dawley strain weighting 180 ±10 g were classified into five groups,(6 rats each) , (-ve) group and four rat groups which administered orally of Piroxicam drug (30 mg/kg) After 24 h fasting as induced-gastric ulcer and reclassified into (+ve) group ,treated with 20 mg/kg b.w of Omeprazole drug , treated with 200 gm date powder , treated with 200 gm of date powder biscuit groups. The study was assigned for 60 days. The results revealed that, the control (+ve) group showed a significant decrease in final weight, weight gain, feed efficiency ratio (FER), catalase (CAT), superoxide dismutase (SOD), glutathione peroxides (GSH),(GSH-R),(GSH-PX),(GSH-ST) compared with control (- ve) group .but showed significant increase in malondialdehyde (MDA) , hydrogen peroxide (H2O2), C-Reactive Protein (CRP), interleukin-6 (ILK) and prostaglandin (PEG2) compared with (- ve) group. The date powder, and date powder biscuit groups showed a significant increase in final , weight gain. food intake, (FER), organ stomach, (CAT), (SOD), (GSH),(GSH-R),(GSH-PX),(GSH-ST),but showed significant decrease in (MDA), (H2O2), (CRP), (ILK), (PEG2) at p<0.001 compared with (+ve) group. The histopathological results showed that treated groups it became nearly normal tissues compared to (+ve) group. It can be recommending that the consumption of date powder and date powder biscuit can lower gastric ulcer with increase of antioxidant enzymes