Background: Mastectomy has many emotional, physical and psychological effects among the affected women which negatively affects not only their body image but also, their self-esteem and self-efficacy. Aim of the study: This study aimed to assess the correlation between body image, self-esteem and self-efficacy among women with mastectomy. Research question: What is the correlation between body image, self-esteem and self-efficacy among women with mastectomy? Design: A descriptive correlational research design was utilized in this study. Setting: This study was conducted at women surgery department at Benha university hospital, Benha City, Qalyubia governorate. Sample: A purposive sample of 100 women with mastectomy was taken from the above mentioned setting. Tools: Tool (1): A structured Interviewing Questionnaire Sheet, Tool (11): Body image scale, Tool (111): Rosenberg Self –esteem scale and Tool (V): Self-efficacy scale. Results: Findings reflected that nearly two thirds of studied women with mastectomy had poor body image. In addition, more than half of them had low levels of self-esteem and self-efficacy. Conclusion: There was a highly statistically significant positive correlation between mean scores of total levels of body image, self-esteem and self-efficacy among the studied women. Recommendation: Psycho-educational program needs to become an integral entity of comprehensive care for all women with mastectomy to enhance their body image, self-esteem and self –efficacy.