Background: Handoff is a vital process for transferring data related to patient care that achieved through effective communication for purpose of ensuring the continuity of patient's care and enhancing nurses' safety attitude. Aim: Assess of evaluative feedback regarding handoff process and its effect on nurses' safety attitude. Study design: A quasi-experimental design with pre-post assessment was carried out in this study. Setting: The study was conducted in medical building departments/ units at Benha University Hospital. Subjects: 119 nurses out from 272 who had more than two years of job experience and selected randomly. Tools: Four tools were used namely, Knowledge Questionnaire Sheet, Observational Checklist, Audit Checklist of Handoff and Safety Attitude Questionnaire. Results: All studied nurses have satisfactory knowledge after implemented of evaluative feedback handoff process compared to less than one third of them had satisfactory knowledge before implementing the evaluative feedback. All of them had adequate level after implementing evaluative feedback, while about one third (33.6%) of the studied nurses had adequate level of performance before the implementation, more than half of them had positive safety attitude before implementing handoff process. While all of them had positive safety attitude after the implementation. Conclusion: Nurses knowledge and performance was improved after providing evaluative feedback regarding handoff process and had positively nurses' safety attitude. Recommendations: Who conduct training program for newly hired nurses about effective handoff process and application of evaluative feedback technique on various areas of patient care.