Background: Hysterectomy was particular type of surgery, which could influence the women life. In fact, decided to undergo hysterectomy was a difficult process for every women, especially psychologically. Aim: This study aimed to explore the relation between body image, self-esteem and quality of life among women after hysterectomy. Design: A descriptive correlational design utilized to fulfil the aimed of this study. Setting: This study   conducted in gynecologically outpatient clinic at Benha University hospital, Benha city, Qalyubia Governorate. Study subject: A purposive sample of (100) women after hysterectomy was taken from the above mentioned setting. The sample was taken during a period of six months, were included in the study. Tools of data collection: Four tools were used to collect the data of this study. Tool (1): Structured Interview Questionnaire sheet to assessed socio-demographic, and medical history of women after hysterectomy. Tool (2): Body Image Scale. Tool (3): Self Esteem Scale. Tool (4): WHO Quality of Life Scale –BREF (WHOQOL- BREF). Results: more than half of the studied women had high concern of their body image and about one-quarter of them, more than half of the studied women had low self-esteem and more than one-quarter of them, less than two third of the studied women had low quality of life and nearly one-quarter of them. Conclusion: There is a highly statistical significant negative correlation between total self-esteem, total body image, and also between total body image and total quality of life among the studied women. Moreover, there is a highly statistical significant positive correlation between total self-esteem of the studied women and their total quality of life. Recommendation: Implementation is initiating comprehensive health educational programs as well as rehabilitation programs for all women following hysterectomy treatment in outpatient's clinic of gynaecological should be held, including psychological, social and physical related issues.