Background: Toxic leadership is ineffective behavior that reflects leadership's negative/ dark side and can negatively affect not only the nurses but also the whole hospital. Hence, nurses' job coping is essential in the present competitive environment. Aim of the study: To identify toxic leadership as perceived by nurses and its relation to their job coping. Study design: A descriptive correlational study design was utilized. Setting: The study was conducted in Critical Care Units at Benha University Hospital. Study subjects: A convenient sample consisting of 295 nurses out of 500 nurses recruited and presented during data collection who had at least one year of job experience and were accepted to participate in the study. Data collection tools: Two tools were used; Tool (I): Toxic Leadership Questionnaire and Tool (II): Job Coping with the Toxic Leader Questionnaire. Results: Three-fifth (59.6%) of the studied nurses had a low perceived level of toxic leadership.  Moreover, less than three-quarters (72.2%) of the studied nurses had a high job coping level.  Conclusion: There was a highly statistically significant positive correlation between total perceived toxic leadership scores and total job coping among nurses. Recommendations: Developing and implementing proper strategies and coping mechanism to deal with toxic leaders.