Background: The prevalence of deep venous thrombosis is significantly higher in pregnant women than in non-pregnant women. Aim of the study: Was to assess knowledge, practices and attitudes of pregnant women regarding deep venous thrombosis. The setting of the study research: Was conducted at obstetrics and gynecological outpatient clinic in Benha University Hospital. Research design: A descriptive was utilized. Sample: A purposive sample of 100 pregnant women were selected according to inclusion criteria. Tools of data collection: Consisted of three tools: Tool I: A structured interviewing questionnaire which included four parts: Demographic characteristic, obstetrics and gynecology history, medical data and pregnant women's knowledge regarding deep venous thrombosis. Tool II: Pregnant women self-reported practices regarding deep venous thrombosis. Tool III: Modified Likert scale for pregnant women's attitudes toward deep venous thrombosis. Results: Less than one quarter of studied pregnant women had good knowledge regarding deep venous thrombosis. More than one third of studied pregnant women had satisfactory self reported practices regarding deep venous thrombosis. One thirds of studied pregnant women had positive attitude toward deep venous thrombosis. Conclusion: There was a highly significant positive correlation between total knowledge, self reported practices, and attitudes scores of studied pregnant women regarding deep venous thrombosis(p>0.001). Recommendations: Application of awareness program to improve pregnant women's knowledge, improve practices and acquired positive attitude regarding deep venous thrombosis.