Aim of the study: The study aimed to evaluate effect of an instructional supportive guideline concerning women reproductive rights on student nurses' perception and satisfaction. Research design: A quasi experimental research (Pre-test/post-test) design. Research setting:  This study was conducted at Faculty of Nursing, Banha University. Sample: A purposive sample, 178 female nursing students in the third academic year. Tools of data collection:  Tool (I) Structured interviewing questionnaire which include three parts (the general characteristics of students, student nurses' knowledge related to women reproductive rights and women reproductive rights attitude assessment scale), Tool (II): Student nurse's satisfaction scale regarding women reproductive rights. Results: One-third (33.7%) of the studied samples had correct total knowledge about women reproductive rights pre intervention. While improved to (87.6%) immediately post and (83.1%) follow up intervention and there was a highly statistically significant difference at (P ≤ 0.001). There is a marked improvement in student nurses' attitude toward women reproductive rights immediate post and follow up intervention compared to pre intervention with a highly statistically significant difference at (P ≤ 0.001). The vast majority (95.5%) of the studied samples satisfied with the guide of women reproductive rights. While the vast minority (4.5%) of them weren't satisfied. Conclusion: The student nurse who attended guideline sessions regarding women reproductive rights shown significant improvement in their perception and satisfaction more than those was not participated. Recommendation: Increase educational supportive guidelines about women reproductive rights for students to improve their knowledge and attitude. Design supportive data instruction booklet to improve the studied sample knowledge and attitude without courses.