Background: Preeclampsia during pregnancy is considered one of the major obstetrical problems in developing countries that cause maternal mortality and preterm birth throughout the world. Aim: The study aimed to evaluate effect of continuous care model on self-care among women with preeclampsia. Research design: Quasi-experimental design (pre-posttest, one group) was utilized. Setting: The study was conducted at Obstetrics and Gynecological out -patient clinic at Benha University hospital. Sampling: A purposive sample of 75 women with preeclampsia was recruited. Tools of data collection: Three tools were included 1) A self-administered questionnaire 2) women's knowledge questionnaire 3) self-care reported practices questionnaire. Results: There was a marked improvement in knowledge and self-care reported practices of studied sample regarding preeclampsia after implementation of the continuous care model with highly statistically significant difference (p<0.001) and there was highly statistically significant positive correlation between total knowledge and total self-care reported practices regarding preeclampsia at pre-intervention and post-intervention phases (p<0.001). Conclusion: Continuous care model had a positive effect on knowledge and self-care among women with preeclampsia. Recommendations: The continuous care model should be integrated as a nursing intervention for promoting women's self-care practices in preeclampsia care.