Background: Cirrhotic ascites is a pathological accumulation of fluid in the peritoneal cavity Cirrhosis is the most common cause of ascites. Aim: This study was aimed to asses coping strategies among patient with cirrhotic ascites. Research design: Descriptive design was utilized in carrying out this study. Setting: Medical Outpatient Clinic at Benha University Hospital in Benha City. Sample: A simple random used to choose patients with cirrhotic ascites which included 146 patients. Tool of data collection. Two tool were uesed. Tool I): A structured interviewing questionnaire which consisted of four parts. Part I): Socio-demographic characteristic of patient with ascites, Part II): Health problems of cirrhotic ascites patients. Part III): Patient's knowledge regarding cirrhotic ascites. Part IV): Practice of patients regarding care of cirrhotic ascites. Tool II): Coping strategies regarding patient care with cirrhotic ascites. Result: 65.1% of studied cirrhotic ascites patients were age group >50 years old with the mean±SD51.92 ± 8.57, 99.3% of them had nervous systems problems of stress, tiredness and sever fatigue, 43.2%of studied cirrhotic ascites patients had average total knowledge level about cirrhotic ascites disease and coping strategies, 56.2% of patients had unsatisfactory total reported practices level, also, 52.7% of them had moderate total level of coping strategies, while, there were highly statistical significant relation between patient's total knowledge level about cirrhotic ascites, total reported practices and their total coping strategies. Conclusion: There were highly statistical significant relation between patient's total knowledge level about cirrhotic ascites, total reported practices and their total coping strategies. Recommendation: Health education program should be developed and implement for cirrhotic ascites patients to enhance their knowledge, practices and coping with the disease.