The garnet bearing muscovite granite (GMG) of Gabal El Magal El Harami along Wadi Nugrus shear zone represents one of important rare metal bearing granites in the South Eastern Desert of Egypt. The Landsat-8 (OLI) remote sensing data, field works, and petrographic investigations revealed that the GMG is emplaced within old continental gneissic units, ophiolite mélange and island arc associations. It forms NNW–SSE trending elongate belt parallel to the famous Wadi Nugrus shear zone. It also appears as small off-shoot dyke-like bodies, and huge semicircular mass with domal shapes. It is essentially composed of pla-gioclase, K-feldspar, quartz, muscovite and garnet. This granite is enriched by some accessory minerals (i.e. garnet spessartine, zircon, fluorite, monazite, xenotime, apatite, iron) and rare metals (i.e. niobium - tantalum, wolframite, cassiterite, beryl). Moreover it is enriched in Ba, Rb, U, Th, K, Nb, but have low Sr, Y. The studied granite intrusion has S-type peraluminous signature and high K-calc alkaline affinity. This intrusion is highly fractionated granite that was formed during the post orogenic times through partial melting of metagraywackes from lower crustal sources under high temperature and pressure conditions.