The present study was conducted to evaluate the possible effect (s) of enriching the broiler chick's diet with Di-Calcium phosphate Nanoparticles (DCaP-NPs) or vitamin D3 on growth performance of broiler chicks. A total number of 240 unsexed one-day-old broiler chicks (Ross) were used. These chicks were randomly and equally distributed into four groups of 60 chicks each, in six replicates (10 chicks each). The first group was fed the basal diet (control group), while the 2nd, 3rd and 4th groups were fed the basal diet enriched with 1-g, 2-g of DCaP-NPs / kg diet, and 1 ml Vitamin D3 / Liter of drinking water, respectively. The experimental period duration was five weeks. The criteria of response on the productive performance. Results showed that at five weeks of age, the best LBW being recorded for chicks that fed the basal diet fortified by 2g/kg (DCaP-NPs) followed by those fed the same diet but with the drinking water containing one ml Vitamin D3 / Liter. Moreover, both T2 and T3 treatment chicks significantly gained more weight than the other groups. Feed consumption was significantly reduced in T3 group than the other groups, while FCR was significantly improved for birds in the T3 group followed by those from the control treatment. After slaughtering carcass weight was significantly heavier in birds from both T2 and T3 treatments than in the control and T1 groups and then were no significant differences in the average values of carcass characteristics and meat analysis among treatments.