There is a lack in developing countries regarding protection of IPR related to plant and pharmaceutical biotechnology compared to developed countries. This study will introduce some successful examples of protection of IPR related to plant and pharmaceutical biotechnology in some developing and developed countries to be guided by them in our country. Objective of the study: 1-Identification of biotechnology, types of biotechnology, impact of biotechnology in economy of nations. 2- Studying different legal means of protection of IPR in plant and pharmaceutical biotechnological fields. 3- Comparative analysis of legal protection of IPR in plant and pharmaceutical biotechnological fields in both developed and developing countries. 4-Measuring the awareness regarding the legal protection of IPR in plant and pharmaceutical biotechnological fields in both developed and developing countries. 5-plant and pharmaceutical biotechnological innovation during crises (e.g., COVID-19) and its impact on fighting diseases and establishing Small and Medium Enterprises and governmental rules in this regard. 6- Crimes of IPR in both developing and developed countries. This study is based on a hypothesis that: there is a difference between developed and developing countries (including Egypt) regarding the protection of IPR in plant and pharmaceutical biotechnological fields and studying this difference will lead us to improve the situation in our country. Comparative Studies of different legal means of IPR protection in plant and pharmaceutical biotechnological fields in both developing and developed countries will be done. (Developing countries: Egypt, Nigeria, India and others – Developed countries: USA, Australia, France and European Countries).