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341806

Rutin: Chemical properties, Pharmacokinetic properties and Biological activities

Article

Last updated: 04 Jan 2025

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Abstract

Recently, due to their excellent safety history and potent therapeutic effects, medicinal plants have gained the interest of researchers. Herbal remedies have been utilized for centuries to both prevent and treat a variety of diseases. Flavonoids, among them, contain polyphenols, which are well known for having a wide range of beneficial medical effects. Rutin is Considered as one of the most important flavonoids and valuable phytochemicals in the pharmaceutical industry. The current study's objective was to evaluate rutin's advantages and disadvantages, utilizing the previously published researches. The pharmacokinetic properties and medical uses of this compound were investigated in details, with an emphasis on new findings, considering its potential relevance to numerous health benefits as antioxidant, hepatoprotective, nephroprotective, neuroprotective, anti-inflammatory, antimicrobial, antidiabetic, antitumor properties and testicular protective action. However, due to some drawbacks, like low absorption and poor solubility, its medicinal use is restricted. Furthermore, strategies to improve the pharmacokinetic profile of rutin are also suggested in light of its possible therapeutic use in the near future

DOI

10.21608/mjvm.2024.341806

Keywords

Rutin, Pharmacokinetic properties, antioxidant, Hepatoprotective, Drug delivery

Authors

First Name

Doaa

Last Name

Madkour

MiddleName

A

Affiliation

Department of Biochemistry and chemistry of nutrition, faculty of veterinary medicine, university of Sadat city, Sadat City, Egypt

Email

doaa.aboelhadid@vet.usc.edu.eg

City

Sadat City

Orcid

0000-0001-7582-335x

First Name

Mohamed

Last Name

Ahmed

MiddleName

-

Affiliation

Department of Biochemistry and chemistry of nutrition, faculty of veterinary medicine, university of Sadat city, Sadat City, Egypt

Email

mohamed.mohamed@vet.usc.edu.eg

City

Sadat City

Orcid

https://orcid.org/00

First Name

Ahmed

Last Name

Elkirdasy

MiddleName

Farag

Affiliation

Department of Biochemistry and Chemistry of nutrition, faculty of veterinary medicine, University of Sadat city, Sadat City, Egypt

Email

ahmed.elkerdasy@vet.usc.edu.eg

City

Sadat City

Orcid

0000-0002-4154-4827

First Name

Sahar

Last Name

Orabi

MiddleName

Hassan

Affiliation

Department of Biochemistry and Chemistry of nutrition, Faculty of veterinary medicine, university of Sadat City, Sadat City, Egypt

Email

sahar.orabi@vet.usc.edu.eg

City

Sadat City

Orcid

0000-0001-8551-9298

First Name

Ahmed

Last Name

Mousa

MiddleName

Abdelmoniem

Affiliation

Department of Biochemistry and Chemistry of Nutrition, Faculty of Veterinary Medicine, University of Sadat City, Sadat City, Egypt

Email

ahmed.mousa@vet.usc.edu.eg

City

Sadat City

Orcid

0000-0001-8058-6176

Volume

4

Article Issue

1

Related Issue

45525

Issue Date

2024-11-01

Receive Date

2024-02-17

Publish Date

2024-11-01

Page Start

26

Page End

34

Print ISSN

2735-458X

Online ISSN

2735-4903

Article File

MJVM_Volume 4_Issue 1_Pages 26-34.pdf

PDF . 487.8kB

Link

https://mjvm.journals.ekb.eg/article_341806.html

Detail API

https://mjvm.journals.ekb.eg/service?article_code=341806

Order

341,806

Type

Research articles

Type Code

1,609

Publication Type

Journal

Publication Title

Matrouh Journal of Veterinary Medicine

Publication Link

https://mjvm.journals.ekb.eg/

MainTitle

Rutin: Chemical properties, Pharmacokinetic properties and Biological activities

Details

Type

Article

Created At

28 Dec 2024