Tax revenue is very dependable in a country's revenue to increase its growth and development. However, taxpayers assume that taxes can reduce a company's profit, primarily since the taxes do not provide direct benefits to companies. This causes them to minimize their tax costs to maximize their profits, either legally or illegally. Therefore, the legal effort taxpayers make to reduce tax burdens and increase profits is called tax avoidance. This study investigates the impact of business strategy, capital intensity, sales growth, and liquidity on tax avoidance. It depends on a sample of 78 companies listed on the EGX100, with 390 observations during the period 2018–2022. The findings show that business strategy has an insignificant impact on tax avoidance practices. Moreover, the results indicate that capital intensity has a significantly positive effect on tax avoidance. The higher the proportion of fixed assets, the greater the depreciation cost, the lower the taxable income, and the lower the tax burden. Therefore, the degree of tax avoidance practices increases with the capital intensity. Furthermore, the results reveal a significantly positive impact of sales growth and liquidity on the practices of tax avoidance. The higher the company's sales growth and liquidity, the greater the financial performance, the higher the profits, and the higher the tax debt. This incentivizes companies to depend on tax avoidance practices to reduce their tax obligations and increase their profits.