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397278

Idiopathic Normal Pressure Hydrocephalus, Case Series

Article

Last updated: 27 Dec 2024

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Abstract

Introduction:
Idiopathic normal pressure hydrocephalus (iNPH) was first described by Dr Hakim and Dr. Adam on1964 in case series described triad of symptoms of difficult walking, dementia and urine incontinence. Diagnosis of iNPH is difficult and should be differentiated from other neurodegenerative diseases.

Objective:
The aim of this study to increase awareness with diagnostic criteria of iNPH that favor the diagnosis and good response to CSF diversion surgery.

Methods:
A retrospective, hospital based descriptive study to evaluate one year outcome of patients were diagnosed with iNPH according to certain clinical and radiological criteria then treated with ventriculoperitoneal shunt in period between 2018to2023. Demographic data were listed, clinical evaluation, radiological specifications, diagnostic measures and algorithm of management were described. Clinical follow up was enrolled.

Results:
Among 69patients were evaluated for possibility of iNPH, 17patients were confirmed their diagnosis. Age mean was 68.5years. 15males(88.2%) and 2females (11.8%). Co-morbidities were multiple lacunar infarcts, diabetes, hypertension, ischemic heart disease, Parkinsonism and Alzheimer's disease. First presentation of all patients was difficult walking with mean duration15.8months. Good response to CSF tapping test after fulfilling the determined radiological criteria. Different degrees of clinical improvement were reported after ventriculoperitoneal shunt insertion.

Conclusion:
Our diagnostic criteria help distinguishing those with iNPH. These criteria could be considered as predictors for good outcome after shunt insertion. Symptoms duration is a cornerstone in determining the degree of improvement. Co-morbidities may affect degree of improvement. Difficult walking is the first symptom to improve. Adjustable valves better to be used.

DOI

10.21608/pajn.2024.294356.1131

Keywords

Idiopathic Normal Pressure Hydrocephalus, difficult walking, Dementia, urine incontinence, CSF diversion

Authors

First Name

Ahmed

Last Name

Elshanawany

MiddleName

-

Affiliation

Neurosurgery department, Faculty of medicine, Assiut university, Assiut, Egypt

Email

aelshanawany@aun.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Elgheriany

MiddleName

-

Affiliation

neurosurgery department, faculty of medicine, Assiut university ,Assiut, Egypt

Email

ahmed.elgheriani@med.au.edu.eg

City

-

Orcid

-

First Name

Farrag

Last Name

Mohammad

MiddleName

-

Affiliation

neurosurgery department, faculty of medicine, Assiut university, Assiut, Egypt

Email

farragmohammad@aun.edu.eg

City

-

Orcid

-

Volume

19

Article Issue

2

Related Issue

52117

Issue Date

2024-12-01

Receive Date

2024-06-01

Publish Date

2024-12-01

Page Start

153

Page End

160

Print ISSN

1319-6995

Online ISSN

2735-4482

Link

https://pajn.journals.ekb.eg/article_397278.html

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https://pajn.journals.ekb.eg/service?article_code=397278

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10

Type

Original Articles

Type Code

1,544

Publication Type

Journal

Publication Title

Pan Arab Journal of Neurosurgery

Publication Link

https://pajn.journals.ekb.eg/

MainTitle

Idiopathic Normal Pressure Hydrocephalus, Case Series

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Article

Created At

27 Dec 2024