The purpose of this research is to enhance the level of energy saving efficiency in light of sustainability practices (lighting, water, trash and purchasing) in hotel sector. Accordingly, this research was based on the analytical approach. The research population is the staff of Sharm El-Sheikh hotels in Egypt. A random stratified sample including managers and employees of five-star hotels was selected. Out of the approximately 770 questionnaires that were sent out, 532 were returned, and 238 were deemed invalid. The results of this research demonstrated the high implementation level of energy-saving efficiency. In addition, there is a very high level of sustainable lighting practices implementation; similarly, there is a high level of sustainable practices implementation related to water, trash, and purchasing. When comparing sustainable practices of lighting, water, trash, and purchasing; sustainable purchasing practices are more closely connected with energy-saving efficiency. Moreover, the level of sustainable lighting practices is correlated with sustainable water (production & consumption), and purchasing practices. Conversely, there is no correlation between the level of sustainable lighting practices and the level of sustainable trash practices. Accordingly, five-star hotels are required to continuously adopt sustainability practices to enhance the level of energy saving efficiency. Finally, this research presents sustainable operational practices to improve the level of sustainable energy-saving efficiency in hotel industry.