Nowadays, advanced technology provides several benefits. Technology is crucial in terms of time, cost, and easy access to information, especially in activities like health tourism. The ability to imitate human intelligence forces us to position Artificial Intelligence (AI) applications with a fundamentally different approach. Artificial intelligence may help produce more focused results in a variety of ways, notably by analyzing the advantages. This paper discusses some of the most significant potential and obstacles associated with applying AI to health tourism. The research aims to explore the utilization of AI as a new trend to strengthen health tourism applications in Egyptian tourist destinations. The methodology of the study was based on descriptive analysis using 117 questionnaires distributed to stakeholders in medical tourism. Several statistical methods were used in the research. The results indicate that the government is standardizing digital infrastructure and data collection in order to improve interoperability and simplify the implementation of AI-powered health services across healthcare systems. This study recommends that the government implement the first AI strategy, the Egypt Artificial Intelligence Strategy, encourage enterprises to invest in AI, and promote public-private collaborations in the fields of AI and health. It is necessary to provide virtual platforms to coordinate health care services before, during, and after they are obtained, allowing customers to have a complete experience, including initial inquiries, coordination with service providers, and follow-up after receiving the service, as well as incorporating sustainable and environmentally friendly practices into medical tourism.