Background: Hospital-acquired pneumonia (HAP) is a significant concern in ICU patients, with a higher morbidity, decease rate, and increased resource use.
Objectives: The study aimed to identify the causative bacteria, antibiotic sensitivity, and resistance among the cases with hospital-acquired pneumonia in Qena university hospitals.
Patients and methods: A cross-sectional study including 70 HAP patients at QUH during the period of one year. The demographics, full clinical evaluations, laboratory investigations, and radiography were collected.
Results: This study involved 70 cases with positive cultures, Elderly patients with chronic chest disease, and COPD exacerbation was the main reason for admission. Bilateral lung consolidation was the commonest radiological finding. Gram-negative bacilli were the most prevalent strain among the study cohort. Gentamycin, chloramphenicol, and amikacin were the most effective antibiotics against blood culture organisms, while imipenem and meropenem were the most effective antibiotics against the sputum culture organisms. Resistance was observed with various antibiotics. The decease rate was 21.43%.
Conclusion: Hospital-acquired pneumonia (HAP) mainly affects older individuals, Gram-negative bacilli were commonly found in cultures, emphasizing their importance in diagnosis. Antibiotic sensitivity and resistance patterns varied, highlighting the necessity for tailored antibiotic selection based on microbiology results.