Background: Determining the right time to extubate is vital. RSBI and diaphragmatic sonography values may provide useful data for predicting the weaning outcome.
Objectives: This study aimed to evaluate the value of RSBI and diaphragm sonography in predicting the weaning failure in mechanically ventilated patients
Patients and methods: This is a prospective observational study including all the mechanically ventilated patients aged >18 years who required invasive mechanical ventilation for more than 24 hours and eligible for weaning criteria. All the demographic data, comorbidities, laboratory investigations were collected. ABG and RSBI were measured during the weaning trial and diaphragmatic ultrasound parameters including [Diaphragmatic excursion, diaphragmatic thickness, and diaphragmatic thickness fraction].
Results: This study included 100 cases. Of all included cases, 21 cases (21%) were successfully weaned and 79 subjects (79%) had weaning failure. PH at the time of admission was considerably higher among the successful weaning cases, Also SO₂ at time of weaning was higher among successful weaning cases. Regarding the weaning parameters, Only RSBI was considerably higher among weaning failure group. DE at time of weaning as it was higher among the successful weaning group (P = 0.00186).
Conclusion: Higher SO2 levels, lower RSBI values, and DTF at weaning were associated with successful weaning, highlighting their potential as predictive factors for weaning outcomes