Background: Subjective wellbeing for those who have schizophrenia is a big challenges which leads to increased psychological distress, worsening depressive symptoms, low self-esteem, unhappiness, conflict, and suffering. Patients with depressive symptoms have a lower quality of life, which is reflected on the extensive burden of schizophrenia and the need for treatment. Purpose: To assess the relation between depressive symptoms and subjective wellbeing among patients with schizophrenia. Design: A descriptive correlational design was utilized. The study was conducted at Meet Khalaf Psychiatric Hospital in Shebin El-kom city, Menoufia Governorate, Egypt. Sample: A purposive sample of 148 patients who had schizophrenia was selected. Instruments: Three instruments were used 1) A structured interview questionnaire to assess socio-demographic characteristics and medical history of  the patients 2) Calgary depression scale for schizophrenia 3) Subjective wellbeing under neuroleptic short version scale. Results: 92.6%  of the studied patients with schizophrenia had low level of subjective wellbeing, 7.4% had moderate level of subjective wellbeing, 85% of the studied patients with schizophrenia suffered from major depressive episode and 96.8% of patients with schizophrenia who had depressive episode had low subjective wellbeing. Conclusion: There was a statistical significant negative correlation between subjective wellbeing and depressive symptoms. Recommendations: comprehensive intervention programs should be developed to improve depressive symptoms and enhance subjective wellbeing among patients with schizophrenia.