Abstract: Background: Post stroke patients have to use coping strategies to regain pre stroke state and enhance their self-efficacy. The Mauk model is a paradigm that focuses on stroke patients with appropriate rehabilitation nursing interventions. Purpose: to evaluate the effect of Mauk nursing rehabilitation model on knowledge, self- efficacy and coping strategies among post stroke elderly patients Design: a quasi-experimental one-group pre-post-test design was used. Setting: the study was conducted at neurology and psychology out-patient clinic, Menoufia University Hospital, Egypt. Sample: A purposive sample of 60 post stroke elderly patients was chosen. Instruments: three instruments were utilized as follow: instrument I: structured interviewing questionnaire, instrument II: ways of coping questionnaire, and instrument III: the stroke self-efficacy questionnaire. Results: The mean total score of stroke knowledge was improved post intervention than pre intervention. There was an increase in the mean total score self-efficacy post intervention than pre intervention. Likewise, there was observed increase in mean total score of ways of coping post intervention than pre intervention. Finally, there was statistical significant correlation between stroke knowledge, ways of coping and stroke self-efficacy total scores post intervention. Conclusion: Implementation of Mauk nursing rehabilitation model have a beneficial effect on improving knowledge, self- efficacy and coping strategies of post stroke elderly patients. Recommendations: Mauk nursing rehabilitation model should become an essential part of the total management plan for post stroke elderly patients.