Cataract remains one of the leading causes of blindness in Egypt and South Africa. Self-care practice is a vital element of daily living and overall well-being of cataract patients. Purpose: To examine effect of patient centered on self-care practices and satisfaction among patients with cataract surgery. Methods: Design: Quasi experimental research design was used. Sample: A consecutive sample of 100 adult patients with cataract was selected for the current study. Instruments: Structured questionnaires assessing patient Socio-demographic data and medical data, observational checklist to assess self-care practices and patient satisfaction questionnaire to determine the satisfaction among cataract patients after surgery. Results: Mean score and standard deviation of baseline patient's practice regarding eye care among studied groups were 3.34±6.25 of study group compared to 3.68±7.66 of control group, While, there were highly statistical significant difference post 1,2 and 3 interventions with P value <0.001. Mean scores of patient's satisfaction post intervention were 39.04±10.98 and 30.60±10.41 among study and control groups respectively. Conclusion: Patient-centered care is effective method to enhance the clinical outcomes of the patient with cataract. Recommendation: Patient centered care should be carried out for cataract patients in ophthalmology setting to increase their knowledge about disease and meet their needs with decrease incidence of complication as vision loss.