Abstract: Background: Challenges in today's work environment require professional competent nurses not only educated well but being creative, have a desire to achieve success, able to work under pressure, and accomplish the organization and personal goals. People with higher creativity tendency personality is influenced by an individual's internal motivation that is, people with high achievement motivation. Purpose: to assess the relation between achievement motivation and creativity among staff nurses. Setting: At Menoufia University Hospital. Sample: A simple random sample of (310) nurses constituted the study sample, two instruments were used which are the Cassidy and Lynn Achievement Motivation Scale and Nurses' Creativity Scale. Results: Three-quarters of the studied nurses had a high level of achievement motivation among the studied nurses and less than two thirds of them had a high level of creativity. Conclusion: There was a highly statistically significant positive strong correlation between achievement motivation and creativity among studied nurses. Recommendations: Conduct training program for head nurses and managers for sustaining achievement motivation and creativity to improve nursing productivity. Perform collaboration protocol between the college of nursing and the hospital to improve nursing creativity and productivity. Repeat this study on a larger probability sample and in various health care sectors to generalize the results.