Background: Maternal obesity has been associated with multiple comorbidities and a higher risk of obstetric and antepartum complications, such as prolonged labor and increased CS. The purpose of the present study was to assess progress of labor among obese women. Design: A descriptive research design was used. Sample: A purposive sample of 370 laboring women was divided into two groups: the obese group and the normal-weight women group. Each group had 185 participants. Settings: The study was conducted at the obstetric departments of the University Hospital and Shebin El-Kom Teaching Hospital in Menoufia Governorate. Instruments of this study were a structured interview questionnaire that included sociodemographic characteristics of women (name, age, education, and occupation), menstrual, obstetric, medical surgical history, weight, height, BMI, etc.) and a partogram to assess the progress of labor. Results: There was a lower mean duration of the latent and active phases (first stage), second stage, and total duration of labor in normal-weight women than in obese women. Also, the mean dose of oxytocin during the first stage of labor was lower in   the normal-weight women than in the obese women. Nearly half of the obese women had CS delivery, compared to only one-third of the normal-weight women. Conclusion: Obese women had prolonged labor duration, slow progress of labor, and a higher rate of CS delivery than normal-weight women. Recommendations Provide health education for obese laboring women during their antenatal counseling, including a healthy diet and exercise to reduce their weight.