Abstract: Hysterectomy has significant negative impact on women physically, psychologically, and socially. Purpose: Evaluate the effect of psychological counseling on depressive symptoms and marital satisfaction among women with hysterectomy. Design: A Quazi experimental research design (study and control group pre/ posttest) was used to achieve the purpose of the study. Setting: This study was carried out at the Obstetrics& Gynecology Outpatient clinic and Surgical Outpatient Clinic in Menoufia University Hospital at Shebin El-kom, Menoufia Governorate, Egypt. Sample: A purposive sample of 100 women who had hysterectomy were divided into two equal groups; study and control group. Instruments: Three instruments were used; (1): A structured interviewing questionnaire: to assess socio- demographic and clinical characteristics (2): Patient Health Questionnaire Depression Scale. (3): Marital satisfaction scale. Results: There was no statistical significant difference between the study group and control group regarding levels of depressive symptoms pre-intervention while there was a significant reduction of the levels of depressive symptoms in the study group than the control group Post intervention. There was no statistical significant difference between the study group and control group regarding levels of marital satisfaction pre-intervention, while there was a statistically significant improvement in the levels of marital satisfaction among the study group than control group post intervention. There was a statistically significant negative correlation between total mean score of marital satisfaction and depressive symptoms at P value <0.001 pre and post intervention. Conclusion:  The psychological counseling has a positive effect on reducing depressive symptoms and improving marital satisfaction among women with hysterectomy. Recommendations: Incorporating psychological counseling into current treatment guidelines as a psychosocial option for women with hysterectomy.