Abstract: Background: Hysterectomy is one of the most common surgeries for treating several uterine diseases.  It is associated with   physical, social, sexual, and psychological consequencies. Purpose: To assess the relationship between marital satisfaction, depressive symptoms and posttraumatic stress disorder among women with hysterectomy. Design:  A descriptive correlational design. Setting: This study was carried out at the Obstetrics& gynecology outpatient clinic and surgical outpatient clinic of Menoufia University Hospital at Shebin El-kom, Menoufia Governorate, Egypt. Sample: A purposive sample of 100 women who had   hysterectomy was selected. Instruments: Four instruments were used; (1): A structured interviewing questionnaire: to assess socio- demographic and clinical characteristics (2): The PTSD Checklist for DSM-5 (3): Marital satisfaction scale. (4): Patient Health Questionnaire Depression Scale. Results: It was revealed that 63% of   studied women had moderate level of marital satisfaction, 66%of them had severe depressive symptoms. The mean of PTSD among the studied women was 51.69±16.36. There was a statistically significant negative correlation between total mean score of PTSD and marital satisfaction. There was a statistically significant positive correlation between total mean score of PTSD and depressive symptoms. Also, there was a statistically significant negative correlation between total mean score of marital satisfaction and depressive symptoms among the studied women. Conclusion: There was a statistically significant negative correlation between total mean score of PTSD and marital satisfaction among the studied women. There was a statistically significant positive correlation between total mean score of PTSD and depressive symptoms among the studied women. Also, there was a statistically significant negative correlation between total mean score of marital satisfaction and depressive symptoms. Recommendations: Educational and psychological counseling programs should be designed for women with hysterectomy to help them cope effectively and prevent the associated psychosocial problems.