Background: Breastfeeding has multiple benefits for mothers and infants which protects against health problems. Telelactation services can sustain breastfeeding at any location through, audio visual technology. Purpose: To investigate effectiveness of telelactation intervention on knowledge, breastfeeding, and relationship between Primiparas and their newborns. Design: Quasi- experimental (control & intervention) design was done at antenatal, delivery and postpartum department of maternity and children Minia university hospital. A randomized sample of fifty four pregnant women per each group was included. Four instruments were used for data collection (breast feeding structured interview, postpartum bonding, mother infant attachment scale and maternal satisfaction of telelactation) questionnaire. Results: Primiparas in the intervention group had higher mean level of knowledge in the intervention group than control group (26.22± 2.62Vs13.74±2.83), primiparas in the intervention group initiated breastfeeding earlier (48.1%) than primiparas in the control group (14.8%)  and  the majority of primiparas in the study group  were satisfied from using telelactation intervention for breastfeeding consultation. Conclusion: The study concluded that telelactation intervention was effective in improving primiparas' knowledge and relationship between Primiparas and their newborns. Recommendation: Telelactation nursing intervention must be used to improve knowledge of Primiparas and solve breastfeeding problems.